{"id":3349,"date":"2019-04-29T12:15:13","date_gmt":"2019-04-29T12:15:13","guid":{"rendered":"https:\/\/lynxee.consulting\/?p=3349"},"modified":"2023-01-26T09:36:21","modified_gmt":"2023-01-26T09:36:21","slug":"europe-efsa-issues-in-physical-and-chemical-properties-and-analytical-methods","status":"publish","type":"post","link":"https:\/\/lynxee.consulting\/en\/europe-efsa-issues-in-physical-and-chemical-properties-and-analytical-methods\/","title":{"rendered":"EUROPE &#8211; EFSA: Issues in Physical and Chemical Properties and Analytical Methods"},"content":{"rendered":"<p style=\"text-align: justify\">EFSA published a technical report on the outcome of expert\u2019s discussions in the area of physical and chemical properties and analytical methods that took place during a Pesticide Peer Review Meeting in November 2018.<\/p>\n<p style=\"text-align: justify\">The main issues identified are related to (<em>i<\/em>) the quality and level of details of the renewal assessment reports and (<em>ii<\/em>) the adherence to the new data requirements, in particular regarding analytical methods and general issues regarding the assessment of the impurity profiles and specifications of the technical material. Discussions which focused mainly on national authorisation of Plant Protection Products (PPP) were not included in this EFSA technical report.<\/p>\n<p>The main topics addressed are:<\/p>\n<ul>\n<li>CRD guidance on physical and chemical properties<\/li>\n<li>Physical-chemical properties of active substances and PPP<\/li>\n<li>Revision of some guidance documents<\/li>\n<li>Methods used for the generation of pre-approval data<\/li>\n<li>Monitoring methods for body fluids and tissues<\/li>\n<li>Evaluation of extraction efficiency in residue analytical methods<\/li>\n<li>Guidance of isomers<\/li>\n<li>Impurities<\/li>\n<li>Five representative batches<\/li>\n<li>Confirmation of analyte identification (active substance, relevant and significant impurities)<\/li>\n<li>LOQ for relevant and significant impurities (5 batch analysis)<\/li>\n<li>Detected but not quantified impurities (5 batch analysis)<\/li>\n<li>Specifications<\/li>\n<li>Microorganisms<\/li>\n<li>Equivalence assessment issues for PPP authorisation at MS level<\/li>\n<\/ul>\n<p style=\"text-align: justify\">For each issue addressed in the document, a background is presented followed by the outcome of discussions reflecting the opinion of the majority of the participating experts and the associated EFSA proposals.<\/p>\n<p>&nbsp;<\/p>\n<p><b>To download: <\/b><\/p>\n<p style=\"text-align: justify\">Outcome of the pesticides peer review meeting on general recurring issues in physical and chemical properties and analytical methods &#8211; <a href=\"https:\/\/efsa.onlinelibrary.wiley.com\/doi\/epdf\/10.2903\/sp.efsa.2019.EN-1623\" target=\"_blank\" rel=\"noopener noreferrer\">EFSA Supporting publication 2019:EN-1623<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><b>See also our previous articles: <\/b><\/p>\n<p><a href=\"https:\/\/lynxee.consulting\/en\/efsa-issues-in-physical-chemical-properties-and-analytical-methods\/\" target=\"_blank\" rel=\"noopener noreferrer\">EFSA: Issues in physical-chemical properties and analytical methods<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><b>Lynxee consulting<\/b>\u2019s team is at your disposal to answer your questions.<\/p>\n<p><b>Contact us!<\/b> <a href=\"https:\/\/lynxee.consulting\/en\/contact\/\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/lynxee.consulting\/en\/contact\/<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h6>Photo credit: crsssteve\/pixabay<\/h6>\n","protected":false},"excerpt":{"rendered":"<p>EFSA published a technical report on the outcome of expert\u2019s discussions in the area of physical and chemical properties and analytical methods that took place during<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":7,"featured_media":3350,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32,33,36],"tags":[143],"class_list":["post-3349","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog-en","category-news","category-regulation","tag-efsa"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>EUROPE - EFSA: Issues in Physical and Chemical Properties and Analytical Methods - Lynxee consulting<\/title>\n<meta name=\"description\" content=\"EFSA published a technical report on the outcome of expert\u2019s discussions in the area of physical and chemical properties and analytical methods that took\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lynxee.consulting\/en\/europe-efsa-issues-in-physical-and-chemical-properties-and-analytical-methods\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"EUROPE - EFSA: Issues in Physical and Chemical Properties and Analytical Methods - Lynxee consulting\" \/>\n<meta property=\"og:description\" content=\"EFSA published a technical report on the outcome of expert\u2019s discussions in the area of physical and chemical properties and analytical methods that took\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lynxee.consulting\/en\/europe-efsa-issues-in-physical-and-chemical-properties-and-analytical-methods\/\" \/>\n<meta property=\"og:site_name\" content=\"Lynxee consulting\" \/>\n<meta property=\"article:published_time\" content=\"2019-04-29T12:15:13+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-01-26T09:36:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/lynxee.consulting\/wp-content\/uploads\/2017\/06\/test-tubes-904546_1920.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1441\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Adrien Margerit\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Adrien Margerit\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/lynxee.consulting\\\/en\\\/europe-efsa-issues-in-physical-and-chemical-properties-and-analytical-methods\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/lynxee.consulting\\\/en\\\/europe-efsa-issues-in-physical-and-chemical-properties-and-analytical-methods\\\/\"},\"author\":{\"name\":\"Adrien Margerit\",\"@id\":\"https:\\\/\\\/lynxee.consulting\\\/#\\\/schema\\\/person\\\/8bd656ad92ca721913ddf5433730d240\"},\"headline\":\"EUROPE &#8211; 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