The public consultation on the guidance document proposed by EFSA for the use of the threshold of toxicological concern (TTC) is opened from 13 November 2018 to 08 January 2019.
This document updates the Scientific Committee opinion of 2012 by considering the latest developments in the field. This is a guidance for EFSA’s scientific panels and staff for the use of the TTC approach as a screening and prioritisation tool for the safety assessment of chemicals, when hazard data are incomplete and human exposure can be estimated as low.
The TTC approach is not applicable where substance-specific data exist or where they are required under EU legislation.
To download: Public consultation: guidance on threshold of toxicological concern approach (en anglais)
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